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Pomegranates contain a powerful dietary antioxidant by the name of punicalagin (which is responsible for more than 50% of the antioxidant potency1), the fruit also stimulates the production of natural antioxidants produced by the body, such as; glutathione, glutathione-peroxidase, and catalase2. The data suggesting decreasing oxidative damage with simultaneous increase in serum NO content support the study of the use of pomegranate extract in order to improve LUTS. In summary, the current clinical trials provide ample evidence for the biological activity of pomegranate extracts in prostate cancer. This study gave for the first time clinical evidence for the accumulation of pomegranate extracts in benign and malignant prostate tissues.
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